Sickle cell anemia in asians

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Because people with SCT are at risk of having a child with sickle cell disease if their partner also has SCT or one of several other abnormal hemoglobin genes, it is important to properly inform them of their status and educate them about possible health problems and reproductive considerations. Key findings from this report are highlighted below and we invite you to read the abstract here. When a person has inherited the sickle hemoglobin gene from one parent and the gene for normal hemoglobin from their other parent, they have sickle cell trait SCT.

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She is looking forward to seeing her extended family, with whom she shares far more than traditions, mannerisms and physical features. The year-old has beta thalassemia, a blood disorder that afflicts two of her cousins and countless others of Mediterranean descent all over the world. Macri's disease is directly linked to her heritage.

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Do you know if you have sickle cell trait? You might not be thinking about having children just yet. Two genes for sickle cell hemoglobin results in sickle cell anemia, the most severe form of sickle cell disease.

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Hemoglobin E trait occurs most frequently among people of Southeast Asian descent. Hemoglobin E trait is rare. If you inherited the hemoglobin E mutation from just 1 of your parents, you typically won't have any symptoms. But you are a carrier of the disease.

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Sickle cell disease is an inherited blood disorder affecting red blood cells. Normal red blood cells contain hemoglobin A. People with sickle cell disease have red blood cells containing mostly hemoglobin S, an abnormal type of hemoglobin.

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Selected to survive. Many people in Southeast Asia--including the Karen--have a mutation that offers some protection against Plasmodium vivax. A mutation common in Southeast Asia that causes anemia also provides some protection against malaria, according to a new study.

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Sickle cell disease is an inherited genetic abnormality of hemoglobin the oxygen-carrying protein found in red blood cells characterized by sickle crescent -shaped red blood cells and chronic anemia caused by excessive destruction of the abnormal red blood cells. Worsening anemia, fever, and shortness of breath with pain in the long bones, abdomen, and chest can indicate sickle cell crisis. A special blood test called electrophoresis can be used to determine whether people have sickle cell disease.

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It is important to know that your genes are not your destiny. There are various environmental and genetic factors working together to shape you. No matter your genetic makeup, maintain ideal blood pressure and glucose levels, avoid harmful alcohol intake, exercise regularly, get regular sleep.

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The American College of Obstetricians and Gynecologists ACOG estimates that more than million persons worldwide are heterozygous carriers of hereditary disorders of hemoglobin Hband at leastaffected homozygotes or compound heterozygotes are born every year. To address this, ACOG has released recommendations for screening and clinical management of hemoglobinopathies during pregnancy. Genetic screening can help physicians identify couples at risk of having children with hemoglobinopathies and counsel them about reproduction and prenatal diagnosis.

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Thalassemias are a group of blood disorders that affect the way the body makes hemoglobin. Hemoglobin is a protein found in red blood cells that carries oxygen throughout the body. It's made up of alpha globin and beta globin.


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